apalutamide will reduce the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications that are CYP3A4 substrates can lead to decreased exposure to these drugs.Diazepam might be quantified in blood or plas